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Erectile dysfunction (or ED), also called maleimpotence, describes a mans inability toachieve and maintain an erection sufficientfor mutually satisfactory sexual intercoursewith his partner. By itself, ED is not a diseasebut more of a signal that something else maybe a problem.
Viagra works best if taken 30-60 minutesbefore sexual activity. Only 1 tablet should betaken per day. It should be taken on anempty stomach. Increasing the dosagebeyond the recommended amounts will notimprove the response and will only result ingreater side effects.
Sildenafil is a vasoactive agent used to treat erectiledysfunction and reduce symptoms in patients with pulmonaryarterial hypertension (PAH).
Sildenafil elevates levels of the second messenger, cGMP, byinhibiting its breakdown via phosphodiesterase type 5 (PDE5).PDE5 is found in particularly high concentrations in the corpuscavernosum, erectile tissue of the penis.
It is also found in the retina and vascular endothelium.
Increased cGMP results in vasodilation which facilitatesgeneration and maintenance of an erection. The vasodilatoryeffects of sildenafil also help reduce symptoms of PAH.
Research sarms 